In a study that explored the underlying processes of female sexual arousal, British-based researchers say they have learned more about how new treatments might be developed to help women with sexual arousal disorder.
In tests on female lab animals, a team from the drug maker Pfizer found that electrical stimulation of the pelvic nerve increases blood flow to the genitalia. This effect was enhanced if the animals were given an experimental drug called UK-414,495, which is believed to block the breakdown of a chemical messenger that plays a crucial role in increasing blood flow during sexual arousal.
Blood flow to the vagina, labia and clitoris increases when a woman is sexually aroused. The increased blood flow causes the organs to swell and the vagina to relax, and also increases vaginal lubrication and genitalia sensitivity, according to background information in a news release about the study.
Women with FSAD find arousal difficult and their genital organs don't respond to sexual stimulation. The condition affects up to 40 percent of women of all ages, the study authors said.
The study findings were published in the April 13 online edition of the British Journal of Pharmacology.
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